| Name | Meaning | Gender |
|---|
| Senthil Vadivelan | Lord Murugan | Boy |
| Serena | Quiet | Girl |
| Sesha | Serpent who symbolizes time | Girl |
| Seshadri | Shesha means - The king of serpents and Adri means - Hill | Boy |
| Sethu | Warrior | Boy |
| Setu | Sacred symbol | Girl |
| Seva | Worship, Service, Attendance, Care | Girl |
| Sevak | Servant | Boy |
| Sevali | | Girl |
| Sevarkodiyon | Lord Murugan | Boy |
| Sevati | White rose | Girl |
| Sevita | Cherished | Girl |
| Sevvel | Lord Murugan | Boy |
| Seyon | Lord Murugan | Boy |
| Shaan | Glory | Boy |
| Shaandilya | Name of a saint | Boy |
| Shaant | Peace and Calm | Boy |
| Shaarav | Pure and Innocent | Boy |
| Shaardul | Tiger | Boy |
| Shaashwat | Eternal | Boy |
| Shaayal | | Boy |
| Shabab | Beauty | Girl |
| Shabalini | Mossy | Girl |
| Shabar | Nectar | Boy |
| Shabari | A tribal devotee of lord Rama | Girl |
| Shabd | | Boy |
| Shabhayata | Culture | Girl |
| Shachi | Wife of lord Indra | Girl |
| Shachin | Lord Indra | Boy |
| Shadab | Fresh | Boy |
| Shagun | Auspicious | Boy |
| Shahalad | Joy | Boy |
| Shahid | Patriot | Boy |
| Shahil | | Boy |
| Shail | Mountain | Boy |
| Shaila | Goddess Parvati, Living in mountain | Girl |
| Shailaja | Name of a river, Goddess Parvati | Girl |
| Shailasha | Goddess Parvati, One who lives in the mountain | Girl |
| Shaildhar | One who holds mountain, Lord Krishna | Boy |
| Shailen | | Girl |
| Shailendra | King of mountains, Himalaya | Boy |
| Shailesh | King of mountains, Himalaya | Boy |
| Shaili | Style, Tradition | Girl |
| Shaistakhan | Polite | Boy |
| Shaivi | Prosperity | Girl |
| Shakambari | Goddess Parvati | Girl |
| Shakini | Goddess Parvati | Girl |
| Shakthi | | Girl |
| Shakti | Goddess Durga, Powerful | Girl |
| Shaktidhar | Lord Shiva, Powerful | Boy |
| Shakuni | Bird, Uncle of Kauravas | Boy |
| Shakunt | Blue jay | Boy |
| Shakuntala | Wife of Dushyant, Brought up by birds | Girl |
| Shakyasinha | Lord Buddha | Boy |
| Shalabh | | Boy |
| Shalaka | Goddess Parvati | Girl |
| Shalakha | Goddess Parvati | Girl |
| Shalalu | Perfume | Girl |
| Shalang | Emperor | Boy |
| Shaligram | Lord Vishnu | Boy |
| Shalik | A Sage | Boy |
| Shalika | Flute | Girl |