| Surname | Mother Tongue | State of Origin |
|---|
| Saini | Hindi | North Indian (Himachal, Rajasthan, Uttarakhand, U.P, Delhi) |
| Soni | Punjabi | Punjab |
| Sonia | | |
| Sony | | |
| Soyam | Meetei; Paite-kuki; Mizo | Manipur |
| Suhan | Punjabi | Punjab |
| Sunny | | |
| Swain | Oriya | Orissa |
| Swami | Kannada, Tulu | Karnataka |
| Swamy | | |
| Swani | | |
| Shahane | Marathi; Konkani | Maharashtra |
| Shaina | | |
| Shan | | |
| Shenoy | Kannada, Tulu | Karnataka |
| Shinu | | |
| Sim | Mizo | Mizoram |
| Simha | | |
| Simi | Kannada, Tulu | Karnataka |
| Sahni | | |
| Saini | Haryanvi | Haryana |
| Saini | Punjabi | Punjab |
| Sinha | Hindi | Uttar Pradesh |
| Sinha; Shingha | Bengali | West Bengal |
| Sohoni | | |
| Som | Bengali | West Bengal |
| Soma | Tamil | Tamil Nadu |
| Somaiya | Gujarati | Gujarat |
| Somu | | |
| Soni | Gujarati | Gujarat |
| Sama | | |
| Sami | | |
| Sana | Bengali | West Bengal |
| Sane | Marathi; Konkani | Maharashtra |
| Sani | | |
| Sanu | | |
| Saumya | | |
| Sawhney | | |
| Sem | | |
| Sen | Bengali | West Bengal |
| Sena | (Christian's) | |
| Sahani | Punjabi | Punjab |